Stability of13C-Urea Breath Test Samples Over Time in the Diagnosis ofHelicobacter pylori

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The 13C urea breath test in the diagnosis of Helicobacter pylori infection.

The urea breath test (UBT) is one of the most important non-invasive methods for detecting Helicobacter pylori infection. The test exploits the hydrolysis of orally administered urea by the enzyme urease, which H pylori produces in large quantities. Urea is hydrolysed to ammonia and carbon dioxide, which diffuses into the blood and is excreted by the lungs. Isotopically labelled CO2 can be dete...

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The C urea breath test in the diagnosis of Helicobacter pylori infection

The urea breath test (UBT) is one of the most important non-invasive methods for detecting Helicobacter pylori infection. The test exploits the hydrolysis of orally administered urea by the enzyme urease, which H pylori produces in large quantities. Urea is hydrolysed to ammonia and carbon dioxide, which diVuses into the blood and is excreted by the lungs. Isotopically labelled CO2 can be detec...

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An optimized 13C-urea breath test for the diagnosis of H pylori infection.

AIM To validate an optimized (13)C-urea breath test ((13)C-UBT) protocol for the diagnosis of H pylori infection that is cost-efficient and maintains excellent diagnostic accuracy. METHODS 70 healthy volunteers were tested with two simplified (13)C-UBT protocols, with test meal (Protocol 2) and without test meal (Protocol 1). Breath samples were collected at 10, 20 and 30 min after ingestion ...

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[Validation of a simplified 13C-urea breath test method for the diagnosis of Helicobacter pylori infection].

OBJECTIVE To validate a simplified 13C-urea breath test (13C-UBT) method for the diagnosis of H. pylori infection. MATERIAL AND METHODS Patients referred for gastrointestinal endoscopy and biopsy were included, and a 13C-UBT was performed after a 6-hour fast. Breath samples were collected in 10 ml glass tubes before and 30 min after the simultaneous administration of 50 mg of 13C-urea and 2 g...

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ژورنال

عنوان ژورنال: Journal of Clinical Laboratory Analysis

سال: 2015

ISSN: 0887-8013

DOI: 10.1002/jcla.21841